M. Maureira, F. Cuadra, M. Cádiz, M. Torres, A. von Marttens, C. Covarrubias, Preparation and osteogenic properties of nanocomposite hydrogel beads loaded with nanometric bioactive glass particles, Biomedical Materials, 16, 045043, 2021. 

C. Corral, D. Altamirano, M. Maureira, J. Martin, C. Covarrubias, Nanoparticles of Bioactive Glass Enhance Biodentine Bioactivity on Dental Pulp Stem Cells, Materials, 14, 2684, 2021. 


J. Bejarano, A.R. Boccaccini, C. Covarrubias, H- Palza, Biodegradable PDLLA scaffolds filled with copper and zinc-doped bioactive glasses for bone repair: effect of metal doping on the in vitro bioactivity, mechanical behavior and degradation, Materials, 13(13), 2908, 2020. 

D Aguilar-Perez, R Vargas-Coronado, JM Cervantes-Uc,… Antibacterial activity of a glass ionomer cement doped with copper nanoparticles, Dental Materials Journal, 2019-046, 2020. 

M Fernández-Arias, M Boutinguiza, J Del Val, C Covarrubias, F Bastias, …, Copper nanoparticles obtained by laser ablation in liquids as bactericidal agent for dental applications, Applied Surface Science, 507, 145032, 2020.

EA Cafferata, C Terraza‐Aguirre, R Barrera, N Faúndez, N González, … Interleukin‐35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis, Journal of Clinical Periodontology, 2020 Jun;47(6):676-688.


C. Covarrubias, A. Agüero, M. Maureira, E. Morellia, G. Escobar, Felipe Cuadra, Cristian Peñafiel, Alfredo Von Marttens, In situ preparation and osteogenic properties of bionanocomposite scaffolds based on aliphatic polyurethane and bioactive glass nanoparticles, Materials Science and Engineering C: Materials for Biological Applications 96 (2019) 642–653.

E.A. Cafferata, C. Alvarez, M. Maureira, F. E. Gonzalez, K.T. Diaz, G. Monasterio, R. Vernal, C. Covarrubias, Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies, Oral Diseases, 1-13, 2019.

Alburquenque, C, Amaro, J, Fuentes, M, Falconer, Mary A, Moreno  C, Covarrubias C, Pinto C, Rodas P, Bucarey SA, Hermosilla, G, Magne, F;Tapia, CV, Protective effect of inactivated blastoconidia in keratinocytes and human reconstituted epithelium against C. albicans infection. Medical mycology, 2019: 457 – 467


Covarrubias, J. P. Durán, M. Maureira, Facile synthesis of lithium carbonate nanoparticles with potential properties for bone repair applications, Materials Letters, 219: 205–208, 2018.

Covarrubias, M. Cádiz, M. Maureira, I. Celhay, F. Cuadra, A. von Marttens Bionanocomposite scaffolds based on chitosan-gelatin and nanodimensional bioactive glass particles: in vitro properties and in vivo bone regeneration, Journal of Biomaterials Applications, 32:1155-1132, 2018.

Mardones J, Gómez ML, Díaz C, Galleguillos C and Covarrubias C. In Vitro Antibacterial Properties of Copper Nanoparticles as Endodontic Medicament against Enterococcus faecalis. Journal of Dentistry & Oral Disorders. 2018; 4(6): 1107.

Covarrubias, D. Trepiana, C. Corral, Synthesis of hybrid copper-chitosan nanoparticles with antibacterial activity against cariogenic Streptococcus mutans, Dental Materials Journal, 8, 37:379-384, 2018.

Corral, P. Negrete, J. Estay, S. Osorio, C. Covarrubias, O.B. de Oliveira Junior, H. Barud, Radiopacity and Chemical Assessment of New Commercial Calcium Silicate-Based Cements, International Journal of Odontostomatology, 12:262-268, 2018.


Correa N, Covarrubias C, Rodas PI, Hermosilla G, Olate VR, Valdés C, Meyer W, Magne F, Tapia CV, Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies. Frontiers in Microbiology, 2017 Jul 11; 8:1292.

Corral Nuñez C, Covarrubias C, Fernandez E, Oliveira OB Junior, Enhanced bioactive properties of BiodentineTM modified with bioactive glass nanoparticles. Journal of Applied Oral Science, 2017, 25:177-185.


C. Covarrubias, M. Mattmann, A. Von Marttens, P. Caviedes, C. Arriagada, F. Valenzuela, J.P. Rodríguez, C. Corral, “Osseointegration properties of titanium dental implants modified with a nanostructured coating based on ordered porous silica and bioactive glass nanoparticles”, Applied Surface Science, 363, 286–295, 2016.

F.J. Aguilar-Pérez, R.F. Vargas-Coronado, J.M. Cervantes-Uc, J.V. Cauich-Rodríguez, C. Covarrubias, M. Pedram-Yazdani, “Preparation and bioactive properties of nano bioactive glass and segmented polyurethane composites”, Journal of Biomaterials Applications, 39: 1362– 1372, 2016.

González JP, Covarrubias C, Cádiz M, Corral C, Cuadra F, Fuentevilla I and Bittner MD, Design of Antimicrobial Release Systems Based on Chitosan and Copper Nanoparticles for Localized Periodontal Therapy, Journal of Dentistry & Oral Disorders. 2016; 2(7): 1035.

E. Boanini, S. Panseri, F. Arroyo, M. Montesi, K. Rubini, A. Tampieri, C. Covarrubias, A. Bigi, Alendronate Functionalized Mesoporous Bioactive Glass Nanospheres, Materials, 9(3), 135, 2016.


C. Covarrubias, F. Arroyo, C. Balanda, M. Neira, A Von Marttens, P. Caviedes, C. Urra, “The effect of the nanoscale structure of nanobioceramics on their in vitro bioactivity and cell differentiation properties”, Journal of Nanomaterials, 2015. vol. 2015, Article ID 526230.


Synthesis of new antibacterial composite coating for titanium based on highly ordered nanoporous silica and silver nanoparticles. M.A. Massa, C. Covarrubias, M. Bittner, I.A. Fuentevilla, P. Capetillo, A. Von Marttens, J.C. Carvajal. Materials Science and Engineering C: Materials for Biological Applications, 45 146–153, 2014.

Synthesis of nanostructured porous silica coatings on titanium and their cell-adhesive and osteogenic differentiation properties.  D. Inzunza, C. Covarrubias, A. Von Marttens, Y. Leighton, J.C. Carvajal, F. Valenzuela, M. Díaz-Dosque, N. Méndez, C. Martínez, A.M. Pino, J.P. Rodríguez, P. Smith, Journal of Biomedical Materials Research Part A, 102A:37-48, 2014.


 V. Tapia, C. Covarrubias, G Rodriguez, R Cabello, I Urzua, M Diaz-Dosque, Synthesis of Nanocomposite Resins with Remineralizing Capability, Caries Research, 47 (5), 456-457.


Preparation and bioactive properties of novel bone-repair bionanocomposites based on hydroxyapatite and bioactive glass nanoparticles. C. Covarrubias, F. Valenzuela, M. Diaz- Dosque, P. Smith, C. Martinez, M. Yazdani-Pedram, Journal of Biomedical Materials Research: Part B – Applied Biomaterials, 100:1672–1682. 2012.


Otras Publicaciones

Enhancing oxidation activity and stability of iso-1-cytochrome c and chloroperoxidase by immobilization in nanostructured supports, S. Águila, R. Vazquez-Duhalt., C. Covarrubias, Gina Pecchi, Joel B. Alderete, Journal of Molecular Catalysis B: Enzymatic, 70, 81–87, 2011.

Catalytic degradation of polyethylene using nanosized ZSM-2 zeolite, C. Covarrubias, F. Gracia, H. Palza, Applied Catalysis A: General, 384, 186-191, 2010.

Preparation of aluminophosphate/polyethylene nanocomposite membranes and their gas permeation properties, C. Covarrubias, R. Quijada, Journal of Membrane Science, 358, 33– 42, 2010.

Catalytic performance of silica-aluminas synthesised with the help of    chitosan biopolymer,

M. Falco, J. Retuert, A. Hidrobo, C. Covarrubias, P. Araya, U. Sedran, Applied Catalysis A: General, 366, 269-274, 2009.Catalytic activity during the preparation of PE/Clay nanocomposites by in situ polymerization with metallocene catalysts, P. Zapata, R. Quijada, C. Covarrubias, E. Moncada, J. Retuert, Journal of Applied Polymer Science, 113, 2368–2377, 2

High catalytic activity of SBA-15–supported metallocene toward ethylene polymerization:  The effect of the ordered porous structure of the support. C. Covarrubias, R. Quijada, Catalysis Communications, 10, 995–1001, 2009.

Synthesis of nanosized ZSM-2 zeolite with potential acid catalytic properties, C.  Covarrubias, R. Quijada, R. Rojas, Microporous and Mesoporous Materials, 117, 118-125 2009.

Ethylene polymerization using dealuminated ZSM-2 zeolite nanocrystals as an active metallocene catalyst support. C. Covarrubias, R. Quijada, R. Rojas, Applied Catalysis A: General, 347, 223-233, 2008.

Removal of Trivalent Chromium Contaminant from Aqueous Media Using FAU-type Zeolite Membranes. C. Covarrubias, M. Tsapatsis, R. Arriagada, R. García, J., Yáñez, H. Ramanan, Z. Lai, Journal of Membrane Science, 312, 163-173, 2008.

Preparation of CPB-Modified FAU Zeolite for Removal of Tannery Wastewater Contaminants. C. Covarrubias, R. García, R. Arriagada, J. Yáñez, Journal of Porous Materials, 15, 491-498, 2008.

Natural Mordenite Derived Zeolites: Synthesis, forming process and their evaluation in Cr(III) removal from tannery wastewater. C. Covarrubias, R. García, R. Arriagada, M.T. Garland, J. Yáñez, Environmental Engineering Science, 24, 1444-1455, 2007.

Cr(III) Exchange on Zeolites Obtained from Kaolin and Natural Mordenite, C. Covarrubias, R. García, R., Arriagada, J. Yáñez, M.T. Garland, Microporous and Mesoporous Materials, 88, 220-231, 2006.

Removal of Chromium (III) from Tannery Effluents, Using a System of Packed Columns of Zeolite and Activated Carbon. C. Covarrubias, R. Arriagada, J. Yáñez, R. García, M.A.S.D. Barros, E.F. Sousa-Aguiar, Journal of Chemical Technology and Biotechnology, 80, 899- 908, 2005.

Sobre el autor

NanoBioMat author

El Laboratorio de Nanobiomateriales es un laboratorio de investigación perteneciente a la Facultad de Odontología de la Universidad de Chile.